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see http://www.sanger.ac.uk/Info/Press/
for the latest on human epigenome project.
[11/28/2004 8:20:00 AM by Mr Krishna Abhay]
see http://biology.plosjournals.org/plosonline/?request=get-document&doi=10.1371/journal.pbio.0020405
This article is very important for the project and will be reffered again and again.It is also an excellent source for references for the new field of epigenomics
[11/28/2004 8:18:00 AM by Mr Krishna Abhay]
The Pilot study for the HEP - the first systematic analysis of methylation - is published on Tuesday 23 November 2004 in PLoS Biology,project started on 27 Nov,Keep watching.
[11/28/2004 8:12:00 AM by Mr Krishna Abhay]
A.Krishna,A.Narayanan,E.C.Keedwell. Neural Networks and Temporal Gene Expression Data. Submitted to EVOBIO 2005 3RD EUROPEAN WORKSHOP ON EVOLUTIONARY COMPUTATION AND BIOINFORMATICS Lausanne, Switzerland, 30 March-1 April 2005.
[11/28/2004 8:11:00 AM by Mr Krishna Abhay]
A.Krishna , A.Narayanan , E.C.Keedwell. Reverse Engineering Gene Networks with Artificial Neural Networks. To be published by Springer Verlag Vienna in conference proceedings of International Conference on Adaptive and Natural ComputiNG Algorithms 21-23 March 2005University of Coimbra Portugal
[11/28/2004 8:09:00 AM by Mr Krishna Abhay]
Stand in awe of the Biological Motherboard
[8/10/2004 8:17:00 PM by Mr Krishna Abhay]
Gaining Novel Biological Insights from The Epigenome Consortium data
Research Area(s):
Research Level: Unspecified   Project Status: Started

In December 1999,an international team created the Human Epigenome Consortium to map the human methylome,They believe that the key that we mammals are different from other classes.
The Human Epigenome Project (HEP) aims to identify, catalogue and interpret genome-wide DNA methylation patterns of all human genes in all major tissues. Methylation is the only flexible genomic parameter that can change genome function under exogenous influence. Hence it constitutes the main and so far missing link between genetics, disease and the environment that is widely thought to play a decisive role in the aetiology of virtually all human pathologies. Methylation occurs naturally on cytosine bases at CpG sequences and is involved in controlling the correct expression of genes. Differentially methylated cytosines give rise to distinct patterns specific for tissue type and disease state. Such methylation variable positions (MVPs) are common epigenetic markers. Like single nucleotide polymorphisms (SNPs), they promise to significantly advance our ability to understand and diagnose human disease.

The Human Epigenome Project (HEP) is a public/private collaboration run by the members of the Human Epigenome Consortium. MVPs identified as part of the HEP will be released publicly in accordance with the HEP data release policy
See http://www.epigenome.org/
The data is recently coming in,this project aims to gain novel biological insights from this data.Those who are interested to become part of this project are welcome.The Human epigenome consortium (HEC)will release the data every 120 days as the project goes along.The HEC propose to finish he epigenome in 5 years.

Project Rating:     4.4 out of 5
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Mr Krishna AbhayUNIVERSITY OF EXETER U.KMentor/AdvisorSend email to this member
Mr jaiswal pushpendraJAYPEE INSTITUTE OF INFORMATION TECHNOLOGY, NOIDA , INDIAMentor/AdvisorSend email to this member

To send emails to all the team members, please click here.
   DateDescription 
18 July 04Project initiated by Mr Krishna Abhay 
10 August 04New member Mr jaiswal pushpendra joined project team 
28 November 04New file uploaded: Important URL and project plan ... 
20 February 05Project progress "deadline of research proposal and literture review shifted to March10 2005,Date of paper to publication shifted to May 24 2005" added by Mr Krishna Abhay 
20 February 05New file uploaded: Revised deadlines ... 
21 October 05New file uploaded: test ... 

System   Membership   Research
Project plan and deadlines with important URL.doc [26 KB]
Category: Biology - Others
Title: Revised deadlines		  

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